Systemic inflammation and disease progression in Alzheimer disease

BACKGROUND: Acute and chronic systemic inflammation are characterized by the systemic production of the proinflammatory cytokine tumor necrosis factor α (TNF-α) that plays a role in immune to brain communication. Previous preclinical research shows that acute systemic inflammation contributes to an...

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Main Authors: Holmes, C, Cunningham, C, Zotova, E, Woolford, J, Dean, C, Kerr, S, Culliford, D, Perry, V H.
Format: Artigo
Sprog:Inglês
Udgivet: American Academy of Neurology 2009
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848584/
https://ncbi.nlm.nih.gov/pubmed/19738171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181b6bb95
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