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Metabolic Network Topology Reveals Transcriptional Regulatory Signatures of Type 2 Diabetes

Type 2 diabetes mellitus (T2DM) is a disorder characterized by both insulin resistance and impaired insulin secretion. Recent transcriptomics studies related to T2DM have revealed changes in expression of a large number of metabolic genes in a variety of tissues. Identification of the molecular mech...

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Detalhes bibliográficos
Main Authors: Zelezniak, Aleksej, Pers, Tune H., Soares, Simão, Patti, Mary Elizabeth, Patil, Kiran Raosaheb
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848542/
https://ncbi.nlm.nih.gov/pubmed/20369014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000729
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