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Impact of dietary amino acids and polyamines on intestinal carcinogenesis and chemoprevention in mouse models
Colon cancer in humans is influenced by both genetic and dietary risk factors. The majority of colon cancers have somatic mutations in the APC (adenomatous polyposis coli) tumour-suppressor gene. Dietary arginine enhances the risk of APC-dependent colon carcinogenesis in mouse models by a mechanism...
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848482/ https://ncbi.nlm.nih.gov/pubmed/17371270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0350322 |
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