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Molecular Dynamics Analysis of the Conformations of a β-hairpin Miniprotein

Molecular Dynamics simulations of a β-hairpin miniprotein, CLN025, were performed to examine the conformational stability of the peptide in H(2)O at 278 K, 300 K, 333 K and 363 K as well as in TFE, MeOH and DMSO at 300 K. CLN025 is a variant of the Chignolin miniprotein, in which the terminal Gly re...

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Detalhes bibliográficos
Main Authors: Hatfield, Marcus P. D., Murphy, Richard F., Lovas, Sándor
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848447/
https://ncbi.nlm.nih.gov/pubmed/20148510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp910465e
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