Population pharmacokinetics and Bayesian estimator of mycophenolic acid in children with idiopathic nephrotic syndrome

AIMS: To develop a population pharmacokinetic model for mycophenolic acid (MPA) in children with idiopathic nephrotic syndrome (INS) treated with mycophenolate mofetil (MMF), identify covariates that explain variability and determine the Bayesian estimator of the area under the concentration–time cu...

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Main Authors: Zhao, Wei, Elie, Valéry, Baudouin, Véronique, Bensman, Albert, André, Jean Luc, Brochard, Karine, Broux, Françoise, Cailliez, Mathilde, Loirat, Chantal, Jacqz-Aigrain, Evelyne
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2010
Assuntos:
Paediatric Clinical Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848409/
https://ncbi.nlm.nih.gov/pubmed/20406220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03615.x
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