Reduced DNA Repair Capacity for Removing Tobacco Carcinogen-Induced DNA Adducts Contributes to Risk of Head and Neck Cancer but not Tumor Characteristics

PURPOSE: Although cigarette smoking and alcohol use are known risk factors for squamous cell carcinoma of head and neck (SCCHN), only a few exposed individuals develop this disease, suggesting an individual susceptibility. In this study, we investigated the associations between genetically determine...

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Detalhes bibliográficos
Main Authors: Wang, Li-E, Hu, Zhibin, Sturgis, Erich M., Spitz, Margaret R., Strom, Sara S., Amos, Christopher I., Guo, Zhaozheng, Qiao, Yawei, Gillenwater, Ann Marie, Myers, Jeffrey N., Clayman, Gary L., Weber, Randal S., El-Naggar, Adel K., Mao, Li, Lippman, Scott M., Hong, Waun Ki, Wei, Qingyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848391/
https://ncbi.nlm.nih.gov/pubmed/20068090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-2156
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