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Effects of thymidine phosphorylase on tumor aggressiveness and 5-fluorouracil sensitivity in cholangiocarcinoma

AIM: To evaluate the role of thymidine phosphorylase (TP) in cholangiocarcinoma using small interfering RNA (siRNA). METHODS: A human cholangiocarcinoma-derived cell line KKU-M139, which has a naturally high level of endogenous TP, had TP expression transiently knocked down using siRNA. Cell growth,...

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Detalhes bibliográficos
Main Authors: Thanasai, Jongkonnee, Limpaiboon, Temduang, Jearanaikoon, Patcharee, Sripa, Banchob, Pairojkul, Chawalit, Tantimavanich, Srisurang, Miwa, Masanao
Formato: Artigo
Idioma:Inglês
Publicado em: The WJG Press and Baishideng 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848371/
https://ncbi.nlm.nih.gov/pubmed/20355241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i13.1631
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