Hydrogen Peroxide is the Major Oxidant Product of Xanthine Oxidase

Xanthine oxidase (XO) is a critical source of reactive oxygen species (ROS) in inflammatory disease. Focus, however, has centered almost exclusively on XO-derived superoxide (O(2)(•−)) while direct H(2)O(2) production from XO has been less well-investigated. Therefore, we examined the relative quant...

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Autori principali: Kelley, Eric E., Khoo, Nicholas K.H., Hundley, Nicholas J., Malik, Umair Z., Freeman, Bruce A., Tarpey, Margaret M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848256/
https://ncbi.nlm.nih.gov/pubmed/19941951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.11.012
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