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Levetiracetam attenuates hippocampal expression of synaptic plasticity-related immediate early and late response genes in amygdala-kindled rats

BACKGROUND: The amygdala-kindled rat is a model for human temporal lobe epilepsy and activity-dependent synaptic plasticity. Hippocampal RNA isolated from amygdala-kindled rats at different kindling stages was analyzed to identify kindling-induced genes. Furthermore, effects of the anti-epileptic dr...

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Autors principals: Christensen, Kenneth V, Leffers, Henrik, Watson, William P, Sánchez, Connie, Kallunki, Pekka, Egebjerg, Jan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848232/
https://ncbi.nlm.nih.gov/pubmed/20105316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-9
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