Different methods for administering 17β-estradiol to ovariectomized rats result in opposite effects on ischemic brain damage

BACKGROUND: Numerous stroke studies have controversially shown estrogens to be either neuroprotective or neurodamaging. The discordant results observed in rat brain ischemia models may be a consequence of discrepancies in estrogen administration modes resulting in plasma concentration profiles far f...

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Autori principali: Strom, Jakob O, Theodorsson, Elvar, Holm, Lovisa, Theodorsson, Annette
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Research article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848231/
https://ncbi.nlm.nih.gov/pubmed/20236508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-39
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