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Ephrin-B2 regulates endothelial cell morphology and motility independently of Eph-receptor binding

The transmembrane protein ephrin-B2 regulates angiogenesis, i.e. the formation of new blood vessels through endothelial sprouting, proliferation and remodeling processes. In addition to essential roles in the embryonic vasculature, ephrin-B2 expression is upregulated in the adult at sites of neovasc...

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Autors principals: Bochenek, Magdalena L., Dickinson, Sarah, Astin, Jonathan W., Adams, Ralf H., Nobes, Catherine D.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848112/
https://ncbi.nlm.nih.gov/pubmed/20233847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.061903
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