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AMPK exerts dual regulatory effects on the PI3K pathway

BACKGROUND: AMP-activated protein kinase (AMPK) is a fuel-sensing enzyme that is activated when cells experience energy deficiency and conversely suppressed in surfeit of energy supply. AMPK activation improves insulin sensitivity via multiple mechanisms, among which AMPK suppresses mTOR/S6K-mediate...

詳細記述

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書誌詳細
主要な著者: Tao, Rong, Gong, Jun, Luo, Xixi, Zang, Mengwei, Guo, Wen, Wen, Rong, Luo, Zhijun
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848036/
https://ncbi.nlm.nih.gov/pubmed/20167101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-5-1
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