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AMPK exerts dual regulatory effects on the PI3K pathway
BACKGROUND: AMP-activated protein kinase (AMPK) is a fuel-sensing enzyme that is activated when cells experience energy deficiency and conversely suppressed in surfeit of energy supply. AMPK activation improves insulin sensitivity via multiple mechanisms, among which AMPK suppresses mTOR/S6K-mediate...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2848036/ https://ncbi.nlm.nih.gov/pubmed/20167101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-5-1 |
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