Transformation of SV40-immortalized human uroepithelial cells by 3-methylcholanthrene increases IFN- and Large T Antigen-induced transcripts

BACKGROUND: Simian Virus 40 (SV40) immortalization followed by treatment of cells with 3-methylcholanthrene (3-MC) has been used to elicit tumors in athymic mice. 3-MC carcinogenesis has been thoroughly studied, however gene-level interactions between 3-MC and SV40 that could have produced the obser...

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Detalhes bibliográficos
Main Authors: Crosby, Lynn M, Moore, Tanya M, George, Michael, Yoon, Lawrence W, Easton, Marilyn J, Ni, Hong, Morgan, Kevin T, DeAngelo, Anthony B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Primary research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848030/
https://ncbi.nlm.nih.gov/pubmed/20178601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-10-4
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