Complementary transcriptomic, lipidomic, and targeted functional genetic analyses in cultured Drosophila cells highlight the role of glycerophospholipid metabolism in Flock House virus RNA replication

BACKGROUND: Cellular membranes are crucial host components utilized by positive-strand RNA viruses for replication of their genomes. Published studies have suggested that the synthesis and distribution of membrane lipids are particularly important for the assembly and function of positive-strand RNA...

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Bibliografske podrobnosti
Main Authors: Castorena, Kathryn M, Stapleford, Kenneth A, Miller, David J
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847973/
https://ncbi.nlm.nih.gov/pubmed/20236518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-183
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