Human Immunodeficiency Virus-1 Nef Expression Induces Intracellular Accumulation of Multivesicular Bodies and Major Histocompatibility Complex Class II Complexes: Potential Role of Phosphatidylinositol 3-Kinase

Nef alters the cell surface expression of several immunoreceptors, which may contribute to viral escape. We show that Nef modifies major histocompatibility complex class II (MHC II) intracellular trafficking and thereby its function. In the presence of Nef, mature, peptide-loaded MHC II were down-mo...

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Pubblicato in:	Mol Biol Cell
Autori principali:	Stumptner-Cuvelette, Pamela, Jouve, Mabel, Helft, Julie, Dugast, Marc, Glouzman, Anne-Sophie, Jooss, Karin, Raposo, Graça, Benaroch, Philippe
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Cell Biology 2003
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284790/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/13679518/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-04-0211
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