A Novel Molecular Diagnostic of Glioblastomas: Detection of an Extracellular Fragment of Protein Tyrosine Phosphatase µ

We recently found that normal human brain and low-grade astrocytomas express the receptor protein tyrosine phosphatase mu (PTPµ) and that the more invasive astrocytomas, glioblastoma multiforme (GBM), downregulate full-length PTPµ expression. Loss of PTPµ expression in GBMs is due to proteolytic cle...

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Autori principali: Burden-Gulley, Susan M, Gates, Theresa J, Burgoyne, Adam M, Cutter, Jennifer L, Lodowski, David T, Robinson, Shenandoah, Sloan, Andrew E, Miller, Robert H, Basilion, James P, Brady-Kalnay, Susann M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847738/
https://ncbi.nlm.nih.gov/pubmed/20360941
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