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Synthesis and in vitro evaluation of cyclic NGR peptide targeted thermally sensitive liposome

The Asn-Gly-Arg (NGR) motif in both cyclic and linear form has previously been shown to specifically bind to CD13/aminopeptidase N that is selectively overexpressed in tumor vasculature and some tumor cells. However, previous versions of cyclic NGR used a liable disulfide bridge between cysteine res...

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Detalhes bibliográficos
Main Authors: Negussie, Ayele H., Miller, Jenna L., Reddy, Goutham, Drake, Steven K., Wood, Bradford J., Dreher, Matthew R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847670/
https://ncbi.nlm.nih.gov/pubmed/20067811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.12.031
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