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Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of sulfur mustard analog 2-chloroethyl ethyl sulfide (CEES)

Sulfur mustard (bis-2-(chloroethyl) sulfide, SM) is a highly reactive vesicating and alkylating chemical warfare agent. A SM analog, 2-chloroethyl ethyl sulfide (CEES) has been utilized to elucidate mechanisms of toxicity and as a screen for therapeutics. Previous studies with SM and CEES have demon...

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Autors principals: O’Neill, Heidi C., White, Carl W., Veress, Livia A., Hendry-Hofer, Tara B., Loader, Joan E., Min, Elysia, Huang, Jie, Rancourt, Raymond C., Day, Brian J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847650/
https://ncbi.nlm.nih.gov/pubmed/20138141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.01.039
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