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Critical role for CuZn-superoxide dismutase in preventing spontaneous intracerebral hemorrhage during acute and chronic hypertension in mice

BACKGROUNDS AND PURPOSE: Superoxide is associated with spontaneous intracerebral hemorrhage (ICH) during hypertension. The goal of this study was to test the hypothesis that changes in superoxide, in genetically altered mice with deletion and overexpression of CuZn-superoxide dismutase (SOD1), modul...

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Detalhes bibliográficos
Main Authors: Wakisaka, Yoshinobu, Chu, Yi, Miller, Jordan D., Rosenberg, Gary A, Heistad, Donald D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847648/
https://ncbi.nlm.nih.gov/pubmed/20150548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.109.569616
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