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Critical role for CuZn-superoxide dismutase in preventing spontaneous intracerebral hemorrhage during acute and chronic hypertension in mice

BACKGROUNDS AND PURPOSE: Superoxide is associated with spontaneous intracerebral hemorrhage (ICH) during hypertension. The goal of this study was to test the hypothesis that changes in superoxide, in genetically altered mice with deletion and overexpression of CuZn-superoxide dismutase (SOD1), modul...

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Autors principals: Wakisaka, Yoshinobu, Chu, Yi, Miller, Jordan D., Rosenberg, Gary A, Heistad, Donald D.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847648/
https://ncbi.nlm.nih.gov/pubmed/20150548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.109.569616
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