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Phosphodiesterase type 1 inhibition improves learning in rats exposed to alcohol during the third trimester equivalent of human gestation

Deficits in learning and memory have been extensively observed in animal models of fetal alcohol spectrum disorders (FASD). Here we use the Morris Maze to test whether Vinpocetine, a Phosphodiesterase type 1 inhibitor, restores learning performance in rats exposed to alcohol during the third trimest...

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Autors principals: Filgueiras, Claudio C., Krahe, Thomas E., Medina, Alexandre E.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847631/
https://ncbi.nlm.nih.gov/pubmed/20219634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.02.046
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