Delayed Resolution of Acute Inflammation in Ulcerative Colitis Is Associated with Elevated Cytokine Release Downstream of TLR4

BACKGROUND: Ulcerative colitis (UC) is widely viewed as a leukocyte-mediated disorder. Although strong evidence implicates an exuberant response to microbial components in its pathogenesis, no intrinsic immune defect has been identified and the underlying pathogenic mechanisms remain obscure. METHOD...

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Autors principals: Rahman, Farooq Z., Smith, Andrew M., Hayee, Bu'Hussain, Marks, Daniel J. B., Bloom, Stuart L., Segal, Anthony W.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847519/
https://ncbi.nlm.nih.gov/pubmed/20360984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009891
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