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Deletion of an enhancer near DLX5 and DLX6 in a family with hearing loss, craniofacial defects, and an inv(7)(q21.3q35)

Precisely regulated temporal and spatial patterns of gene expression are essential for proper human development. Cis-acting regulatory elements, some located at large distances from their corresponding genes, play a critical role in transcriptional control of key developmental genes and disruption o...

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Hlavní autoři: Brown, Kerry K., Reiss, Jacob A., Crow, Kate, Ferguson, Heather L., Kelly, Chantal, Fritzsch, Bernd, Morton, Cynthia C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847447/
https://ncbi.nlm.nih.gov/pubmed/19707792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-009-0736-4
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