Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice

Levels of the necessary nutrient vitamin C (ascorbate) are tightly regulated by intestinal absorption, tissue accumulation, and renal reabsorption and excretion. Ascorbate levels are controlled in part by regulation of transport through at least 2 sodium-dependent transporters: Slc23a1 and Slc23a2 (...

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Main Authors: Corpe, Christopher P., Tu, Hongbin, Eck, Peter, Wang, Jin, Faulhaber-Walter, Robert, Schnermann, Jurgen, Margolis, Sam, Padayatty, Sebastian, Sun, He, Wang, Yaohui, Nussbaum, Robert L., Espey, Michael Graham, Levine, Mark
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847422/
https://ncbi.nlm.nih.gov/pubmed/20200446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39191
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