Analysis of the Staphylococcus aureus DgkB Structure Reveals a Common Catalytic Mechanism for the Soluble Diacylglycerol Kinases

Soluble diacylglycerol (DAG) kinases function as regulators of diacylglycerol metabolism in cell signaling and intermediary metabolism. We report the first structure of a DAG kinase, DgkB from Staphylococcus aureus, both as the free enzyme and in complex with ADP. The molecule is a tight homodimer,...

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Bibliographic Details
Main Authors: Miller, Darcie J., Jerga, Agoston, Rock, Charles O., White, Stephen W.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847398/
https://ncbi.nlm.nih.gov/pubmed/18611377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.03.019
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