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Self-assembled gold nanoparticle molecular probes for detecting proteolytic activity in vivo

Target-activatable fluorogenic probes based on gold nanoparticles (AuNPs) functionalized with self-assembled heterogeneous monolayers of dye-labeled peptides and poly(ethylene glycol) have been developed to visualize proteolytic activity in vivo. A one-step synthesis strategy that allows simple gene...

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Detalhes bibliográficos
Main Authors: Mu, C. Jenny, LaVan, David A., Langer, Robert S., Zetter, Bruce R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847389/
https://ncbi.nlm.nih.gov/pubmed/20146506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn9017334
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