Activity of KRM-1648, a new benzoxazinorifamycin, against Mycobacterium tuberculosis in a murine model.

The activity of KRM-1648 was evaluated in a murine model of tuberculosis. Approximately 10(7) viable Mycobacterium tuberculosis ATCC 35801 organisms were given intravenously to 4-week-old female outbred mice. Treatment was started 1 week postinfection and given by gavage for 4 weeks. Viable-cell cou...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Klemens, S P, Grossi, M A, Cynamon, M H
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1994
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284725/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7840552/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.10.2245
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