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Finding regulatory DNA motifs using alignment-free evolutionary conservation information

As an increasing number of eukaryotic genomes are being sequenced, comparative studies aimed at detecting regulatory elements in intergenic sequences are becoming more prevalent. Most comparative methods for transcription factor (TF) binding site discovery make use of global or local alignments of o...

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Bibliografiske detaljer
Main Authors: Gordân, Raluca, Narlikar, Leelavati, Hartemink, Alexander J.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847231/
https://ncbi.nlm.nih.gov/pubmed/20047961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1166
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