Effects of abasic sites on structural, thermodynamic and kinetic properties of quadruplex structures

Abasic sites represent the most frequent lesion in DNA. Since several events generating abasic sites concern guanines, this damage is particularly important in quadruplex forming G-rich sequences, many of which are believed to be involved in several biological roles. However, the effects of abasic s...

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Main Authors: Esposito, Veronica, Martino, Luigi, Citarella, Giuseppe, Virgilio, Antonella, Mayol, Luciano, Giancola, Concetta, Galeone, Aldo
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Structural Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847214/
https://ncbi.nlm.nih.gov/pubmed/20026588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1087
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