Reduced hippocampal neurogenesis in the GR(+/−) genetic mouse model of depression

Glucocorticoid receptor (GR) heterozygous mice (GR(+/−)) represent a valuable animal model for major depression. GR(+/−) mice show a depression-related phenotype characterized by increased learned helplessness on the behavioral level and neuroendocrine alterations with hypothalamo-pituitary-adrenal...

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Detalhes bibliográficos
Main Authors: Kronenberg, Golo, Kirste, Imke, Inta, Dragos, Chourbaji, Sabine, Heuser, Isabella, Endres, Matthias, Gass, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: D. Steinkopff-Verlag 2009
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847168/
https://ncbi.nlm.nih.gov/pubmed/19644729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00406-009-0036-y
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