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Pure nucleoside enantiomers of beta-2',3'-dideoxycytidine analogs are selective inhibitors of hepatitis B virus in vitro.

(-)-beta-L-2',3'-Dideoxycytidine (beta-L-DDC), (+)-beta-D-2',3'-dideoxycytidine (beta-D-DDC), (-)-beta-L-2',3'-dideoxy-5-fluorocytidine (beta-L-FDDC), (-)-beta-L-2',3'-dideoxy-5-fluoro-3'-thiacytidine (beta-L-FTC), and (+)-beta-D-1,3-dioxolane-5-fluorocytidine (beta-D-FDOC) were evaluated for their...

Ausführliche Beschreibung

Gespeichert in:
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Schinazi, R F, Gosselin, G, Faraj, A, Korba, B E, Liotta, D C, Chu, C K, Mathé, C, Imbach, J L, Sommadossi, J P
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1994
Schlagworte:
Research Article
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284704/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7811039/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.9.2172
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