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Bottleneck Effects on Vaccine-Candidate Antigen Diversity of Malaria Parasites in Thailand

A number of cell surface antigens of the infective stages of malaria parasites (genus Plasmodium) have been proposed as vaccine candidates, but high levels of polymorphism at the loci encoding these antigens are problematic for vaccine effectiveness. In order to test for the effects of anti-malarial...

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Autors principals: Jongwutiwes, Somchai, Putaporntip, Chaturong, Hughes, Austin L.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847032/
https://ncbi.nlm.nih.gov/pubmed/20199765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.02.062
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