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Vitamin D(3)-driven signals for myeloid cell differentiation - Implications for differentiation therapy

Primitive myeloid leukemic cell lines can be driven to differentiate to monocyte-like cells by 1α,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), and, therefore, 1,25(OH)(2)D(3) may be useful in differentiation therapy of myeloid leukemia and myelodysplastic syndromes (MDS). Recent studies have provided...

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Autors principals: Hughes, Philip J, Marcinkowska, Ewa, Gocek, Elzbieta, Studzinski, George P, Brown, Geoffrey
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847023/
https://ncbi.nlm.nih.gov/pubmed/19811822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2009.09.010
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