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Contribution of enzymatic properties, cell permeability, and enzyme expression to microbiological activities of beta-lactams in three Bacteroides fragilis isolates that harbor a metallo-beta-lactamase gene.

The metallo-beta-lactamase gene, ccrA, has been cloned from three clinical isolates of Bacteroides fragilis, TAL3636, QMCN3, and QMCN4. Although all three isolates harbored a gene encoding a potent beta-lactamase, the MICs of benzylpenicillin, piperacillin, cefotaxime, ceftazidime, imipenem, and bia...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Rasmussen, B A, Yang, Y, Jacobus, N, Bush, K
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284694/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7811029/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.9.2116
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