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Pharmacokinetics of fluconazole in cerebrospinal fluid and serum of rabbits: validation of an animal model used to measure drug concentrations in cerebrospinal fluid.

Complete concentration-time data describing the pharmacokinetics of fluconazole in the cerebrospinal fluid (CSF) following a single dose are not available for humans or animals. We studied the pharmacokinetics of fluconazole with an indwelling intracisternal needle as described by R.G. Dacey and M.A...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Madu, A, Cioffe, C, Mian, U, Burroughs, M, Tuomanen, E, Mayers, M, Schwartz, E, Miller, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1994
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284693/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7811028/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.9.2111
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