Tax gene expression and cell cycling but not cell death are selected during HTLV-1 infection in vivo

BACKGROUND: Adult T cell leukemia results from the malignant transformation of a CD4(+ )lymphoid clone carrying an integrated HTLV-1 provirus that has undergone several oncogenic events over a 30-60 year period of persistent clonal expansion. Both CD4(+ )and CD8(+ )lymphocytes are infected in vivo;...

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Bibliografiske detaljer
Main Authors: Zane, Linda, Sibon, David, Jeannin, Lionel, Zandecki, Marc, Delfau-Larue, Marie-Hélène, Gessain, Antoine, Gout, Olivier, Pinatel, Christiane, Lançon, Agnès, Mortreux, Franck, Wattel, Eric
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846874/
https://ncbi.nlm.nih.gov/pubmed/20222966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-17
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