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Nanoscopy of the cellular response to hypoxia by means of fluorescence resonance energy transfer (FRET) and new FRET software

BACKGROUND: Cellular oxygen sensing is fundamental to all mammalian cells to adequately respond to a shortage of oxygen by increasing the expression of genes that will ensure energy homeostasis. The transcription factor Hypoxia-Inducible-Factor-1 (HIF-1) is the key regulator of the response because...

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Detalhes bibliográficos
Main Authors: Wotzlaw, Christoph, Gneuss, Silke, Konietzny, Rebecca, Fandrey, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846870/
https://ncbi.nlm.nih.gov/pubmed/20205712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-5036-3-5
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