Association of IL-4RA single nucleotide polymorphisms, HLA-DR and HLA-DQ in children with Alternaria-sensitive moderate-severe asthma

BACKGROUND: Asthma afflicts 6% to 8% of the United States population, and severe asthma represents approximately 10% of asthmatic patients. Several epidemiologic studies in the United States and Europe have linked Alternaria sensitivity to both persistence and severity of asthma. In order to begin t...

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Detalhes bibliográficos
Main Authors: Knutsen, Alan P, Vijay, Hari M, Kariuki, Barbara, Santiago, Luis A, Graff, Ralph, Wofford, Jonathan D, Shah, Maulik R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846861/
https://ncbi.nlm.nih.gov/pubmed/20298583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-7961-8-5
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