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A Tandem Prins/Schmidt Reaction Approach to Marine Alkaloids: Formal and Total Syntheses of Lepadiformines A and C

[Image: see text] The tricyclic core of the cylindricine or lepadiformine families of alkaloid natural products was assembled via a Prins addition/intramolecular Schmidt rearrangement under Lewis acid conditions. Both single-pot and two-stage variations of this process were examined, with particular...

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Detalhes bibliográficos
Main Authors: Meyer, Angelica M., Katz, Christopher E., Li, Sze-Wan, Velde, David Vander, Aubé, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846845/
https://ncbi.nlm.nih.gov/pubmed/20178342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol100113r
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