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Pseudomonas aeruginosa Porin OprF Exists in Two Different Conformations

The major nonspecific porin of Pseudomonas aeruginosa, OprF, produces a large channel yet allows only a slow diffusion of various solutes. Here we provide an explanation of this apparent paradox. We first show, by introduction of tobacco etch virus protease cleavage site in the middle of OprF protei...

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Bibliografiske detaljer
Main Authors: Sugawara, Etsuko, Nestorovich, Ekaterina M., Bezrukov, Sergey M., Nikaido, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846725/
https://ncbi.nlm.nih.gov/pubmed/16595653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M600680200
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