Stimulation of genetic instability and associated large genomic rearrangements in Streptomyces ambofaciens by three fluoroquinolones.

In Streptomyces ambofaciens NSA2002, pigmented wild-type colonies spontaneously give rise to pigment-negative (Pig-) mutants at a frequency of about 0.5%. This genetic instability is related to large deletions which can be associated with amplifications of DNA sequences. The influence of three fluor...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Volff, J N, Vandewiele, D, Decaris, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284672/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7811007/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.9.1984
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