In vivo efficacy of a broad-spectrum cephalosporin, ceftriaxone, against penicillin-susceptible and -resistant strains of Streptococcus pneumoniae in a mouse pneumonia model.

The increasing emergence of penicillin-resistant (Pr) strains of Streptococcus pneumoniae could pose a therapeutic problem in the next few years. Ceftriaxone (CRO), a broad-spectrum cephalosporin, exhibits a smaller increase in MICs against Pr S. pneumoniae strains than amoxicillin (AMO) (usually re...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Moine, P, Vallée, E, Azoulay-Dupuis, E, Bourget, P, Bédos, J P, Bauchet, J, Pocidalo, J J
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284667/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7811003/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.9.1953
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