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Reaction Discovery Using Microfluidic-Based Multidimensional Screening of Polycyclic Iminium Ethers

Polycyclic iminium ethers are ambident electrophilic intermediates that react with a range of nucleophiles in a highly condition-dependent manner to afford densely functionalized lactams. In an effort to expand the scope of reactivity and assist in the generation of new chemotypes from these interme...

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Detalhes bibliográficos
Main Authors: Treece, Jennifer L., Goodell, John R., Vander Velde, David, Porco, John A., Aubé, Jeffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846649/
https://ncbi.nlm.nih.gov/pubmed/20163127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo100087h
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