Subunit specificity of mutations that confer resistance to nonnucleoside inhibitors in human immunodeficiency virus type 1 reverse transcriptase.

We constructed plasmid vectors that simultaneously express both the p66 and p51 subunits of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) in Escherichia coli. These vectors allow us to generate HIV-1 RT heterodimers in which either the p66 or the p51 subunit has the wild-typ...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Boyer, P L, Ding, J, Arnold, E, Hughes, S H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284661/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7529011/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.9.1909
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