Contribution of VanY D,D-carboxypeptidase to glycopeptide resistance in Enterococcus faecalis by hydrolysis of peptidoglycan precursors.

The vanR, vanS, vanH, vanA, and vanX genes of enterococcal transposon Tn1546 were introduced into the chromosome of Enterococcus faecalis JH2-2. Complementation of this portion of the van gene cluster by a plasmid encoding VanY D,D-carboxypeptidase led to a fourfold increase in the vancomycin MIC (f...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Arthur, M, Depardieu, F, Snaith, H A, Reynolds, P E, Courvalin, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284659/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7810996/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.9.1899
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