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Vascular Endothelial Growth Factor Receptor-2 Inhibition Promotes Cell Death and Limits Endothelial Cell Proliferation in a Neonatal Rodent Model of Stroke

BACKGROUND AND PURPOSE: Recent studies in neonatal rodent stroke models suggest that recovery is due in part to upregulation of hypoxia-inducible factor-1-a and its downstream target, vascular endothelial growth factor. Vascular endothelial growth factor is upregulated after a hypoxic insult and is...

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Autors principals: Shimotake, Janet, Derugin, Nikita, Wendland, Michael, Vexler, Zinaida S., Ferriero, Donna M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846555/
https://ncbi.nlm.nih.gov/pubmed/20101028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.109.564229
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