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Synthesis and Antimicrobial Evaluation of 5-Iodopyrimidine Analogs
4-Substituted-5-iodo-2-benzylthiopyrimidines were prepared efficiently in three steps. 2-Benzylthiopyrimidine on iodination in presence of base gave 5-iodo-2-benzylthiopyrimidine (1), which on chlorination with excess of POCl(3) furnished 4-chloro-5-iodo-2-benzylthiopyrimidine (2). Reaction of 2 wit...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Medknow Publications
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2846474/ https://ncbi.nlm.nih.gov/pubmed/20376222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0250-474X.59551 |
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