BMP type I receptor inhibition reduces heterotopic ossification

Fibrodysplasia ossificans progressiva (FOP) is a congenital disorder of progressive and widespread postnatal ossification of soft tissues1–4 and is without known effective treatments. Affected individuals harbor conserved mutations in the ACVR1 gene that are thought to cause constitutive activation...

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Bibliografiset tiedot
Päätekijät: Yu, Paul B, Deng, Donna Y, Lai, Carol S, Hong, Charles C, Cuny, Gregory D, Bouxsein, Mary L, Hong, Deborah W, McManus, Patrick M, Katagiri, Takenobu, Sachidanandan, Chetana, Kamiya, Nobuhiro, Fukuda, Tomokazu, Mishina, Yuji, Peterson, Randall T, Bloch, Kenneth D
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846458/
https://ncbi.nlm.nih.gov/pubmed/19029982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1888
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