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How Nature Morphs Peptide Scaffolds into Antibiotics

[Image: see text] The conventional notion that peptides are poor candidates for orally available drugs because of protease-sensitive peptide bonds, intrinsic hydrophilicity, and ionic charges contrasts with the diversity of antibiotic natural products with peptide-based frameworks that are synthesiz...

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Detalhes bibliográficos
Main Authors: Nolan, Elizabeth M., Walsh, Christopher T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846400/
https://ncbi.nlm.nih.gov/pubmed/19058272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800438
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