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How Nature Morphs Peptide Scaffolds into Antibiotics
[Image: see text] The conventional notion that peptides are poor candidates for orally available drugs because of protease-sensitive peptide bonds, intrinsic hydrophilicity, and ionic charges contrasts with the diversity of antibiotic natural products with peptide-based frameworks that are synthesiz...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2846400/ https://ncbi.nlm.nih.gov/pubmed/19058272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800438 |
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