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Protrusion of a Virtual Model Lamellipodium by Actin Polymerization: A Coarse-grained Langevin Dynamics Model

We report the development of a coarse-grained Langevin dynamics model of a lamellipodium featuring growing F-actin filaments in order to study the effect of stiffness of the F-actin filament, the G-actin monomer concentration, and the number of polymerization sites on lamellipodium protrusion. The v...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jeon, Junhwan, Alexander, Nelson R., Weaver, Alissa M., Cummings, Peter T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846375/
https://ncbi.nlm.nih.gov/pubmed/20351797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10955-008-9600-5
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