Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen

To understand the T cell response to prostate cancer, we created transgenic mice that express a model antigen in a prostate-restricted pattern and crossed these animals to TRAMP mice that develop spontaneous prostate cancer. Adoptive transfer of prostate-specific CD4 T cells shows that, in the absen...

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Main Authors: Drake, Charles G., Doody, Amy D.H., Mihalyo, Marianne A., Huang, Ching-Tai, Kelleher, Erin, Ravi, Sowmya, Hipkiss, Edward L., Flies, Dallas B., Kennedy, Eugene P., Long, Meixiao, McGary, Patrick W., Coryell, Lee, Nelson, William G., Pardoll, Drew M., Adler, Adam J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2005
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846360/
https://ncbi.nlm.nih.gov/pubmed/15766662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2005.01.027
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